| Title | Weekend | Gross | |
|---|---|---|---|
| 1 | Alice in Wonderland | $116.3M | $116.3M |
| 2 | Brooklyn's Finest | $13.5M | $13.5M |
| 3 | Shutter Island | $13.3M | $95.8M |
| 4 | Cop Out | $9.1M | $32.4M |
| 5 | Avatar | $7.7M | $720.2M |
| 6 | The Crazies | $7M | $27.4M |
| 7 | Valentine's Day | $4.3M | $106.4M |
| 8 | Crazy Heart | $3.4M | $29.6M |
| 9 | Dear John | $2.9M | $76.7M |
| 10 | The Wolfman | $4.3M | $57.4M |
